Does Sulfite Cause Red Wine Headaches?

Every now and then someone tells me theytypically a symptom of sulfite reactions. Despite the
don’t like red wine and prefer white wineseriousness of some reactions, the FDA has reported
because the sulfites in red wine gives them aonly 19 sulfite related deaths since 1990. None of
headache – commonly known as the Red Winethese deaths were related to red wine.
Headache (RWH). The label “WARNING: ContainsResearchers in Australia studied a group of people
Sulfites” seems to justify their claim. Thewho were very sensitive to sulfites. The researchers
question is do the sulfites in red wine really causegave these people a drink that contained 300 mg/liter
headaches?of sulfites, much higher than the amount typically in
Sulfites are used as a natural preservative in wine.red wine. Only 4 test subjects out of 24 showed an
The reason it is called a “natural”asthmatic response. None of the subjects responded
preservative is because sulfites are a naturaladversely to drinks with 100 mg/liter. This study
byproduct of the fermentation process. More sulfitepublished in Thorax (2001 Oct; 56 (10):763-9),
is often added by the winery as potassiumshowed that “only a small number of wine
metabisulfite. This added preservative allows the winesensitive asthmatic patients responded to a single
to age over many years; otherwise it would quicklydose challenge with sulfited wine under laboratory
turn to vinegar. Organic wines have this agingconditions. This may suggest that the role of
problem.sulphites [sic] and / or wine in triggering asthmatic
All red wine contains sulfites, even the ones labeledresponses has been overestimated.”
“no sulfite added”. So do all white winesThis still does not answer the question about RWH.
– white wines have much more sulfite onThe fact is no current peer reviewed medical
average. All wines contain 40-80 mg/liter of sulfitesresearch links sulfites to headaches. This does not
on average. Organic wines contain less, but they stillmean that red wine does not cause headaches for
have sulfite in them. You cannot make wine withoutsome people. There is research that shows that red
making sulfites. It does not matter which country thewine does cause headaches for some, the culprit
wine originates from. The US and Australia list sulfitehowever is not the sulfites.
warnings on their labels, but the Europeans are notMost recent medical studies believe that
required to do so. European wines still contain theprostaglandins, hormone-like substances, may be
same amount of sulfites.responsible for the production of some types of pain
Sulfites are also used in dried fruit; no one claims thatand inflammation and could be the culprit in RWH.
they got a headache from a bag of dried apricots.Herbert Kaufman, M.D. and Dwight Starr, M.D. from
Pancake syrup typically contains more sulfite than redMt. Zion Hospital and Medical Center showed a
wine. The human body also produces sulfites throughsignificant decrease in headaches in subjects prone to
normal biochemical processes, about 1000 mg perRWH and given prostaglandin inhibitors.
day.If you are still in doubt, try eating a bag of dried
Some studies have shown that some people canorange apricots. These are heavily sulfited. If you
have strong reactions to sulfites. Slightly less than 1%don’t experience the very rare headache, or the
of the population lacks an enzyme to break downmuch more common respiratory problems, you are
the sulfites. In comparison, peanut allergies affectnot sensitive to sulfites. The best advice is to keep a
about 4% of the population.journal of red wines that you try. Note which wines
For these people the inability to break down sulfitesgive you a headache, and which wines that have no
can be a life threatening problem – much moreeffect. In the future, drink the red wines that do not
serious than a headache. Symptoms typically includegive you a headache.
restricted breathing to varying degrees, especially inOne last note, the headache you get from several
asthmatics prescribed steroids. Skin rashes, itching orwines the night before is called a hangover. Those
nausea are rarer symptoms, but headaches are notcan be avoided by not drinking as much!